Luttrell was born in Toronto, Ontario to a Tanzanian mother and an American father. She is the youngest of four daughters. She is able to speak French and Swahili.
Luttrell is best known for her role as Kara on the children's television series Shining Time Station, and the voice of Keesha Franklin on The Magic School Bus. In 1997, she starred as Emelie Robeson on The New Ghostwriter Mysteries.